From John F. Kennedy Airport: Take Van Wyck Expressway to 495 West (Long Island Expressway). Continue to the Midtown Tunnel and exit on 3rd Avenue. Turn left on 48th Street and Lexington Avenue.
From LaGuardia Airport: Take Grand Central Parkway West to the Triborough Bridge. Then take FDR Drive South to 49th Street Exit. Continue on 49th Street to Lexington and turn left to 48th Street.
From Newark Airport:Take New Jersey Turnpike North to Lincoln Tunnel to 42nd Street. Make a left on 3rd Avenue and continue to 48th Street.
From Westchester Airport: Take the I-87 S/Deegan Expy exit toward Triboro Bridge. Take the exit onto I-278 W toward Triboro Bridge/Manhattan Queens and exit toward FDR Drive. Merge onto Robert F Kennedy Bridge and take exit 8 toward I-495 Midtown Tunnel. Turn left on 48th and Lexington.